Oxandrolone (also known as anavar) is an oral 17-alpha-alkylated steroid, modification of dihydrotestosterone. It was firstly synthesized for the treatment of debilitated HIV-infected patients, for persons with Turner syndrome, anaemia, for bones strengthening and recovery from burns. Oxandrolone first came to be in the 1960’s and was brought to the market by G.D. Searle & co under the name Anavar.
Oxandrolone possesses many functions that are beneficial but it is in its ability to reduce Sex Hormone Binding Globulin (SHBG) glucocorticoid hormones and increases in nitrogen retention that make it so valuable. An increase in nitrogen retention creates a more apt anabolic environment where as a reduced one leads to catabolism. The decrease in SHBG promotes higher levels of free testosterone and also frees any and other anabolic steroidal hormones from being bound.
Oxandrolone does not yield to aromatization and is not estrogenic itself. This drug is beloved by athletes, who prepares for competition in strength and endurance sports, where lean muscle without water and fat are needed.